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Adderall and seroquel for sleep problems," but the authors, led by Dr. R. Almeida-Souza in Brazil, could find no credible evidence.
They suggested that many sleep disorders are linked more with the immune system than sleep brain, in other words, that the symptoms of anxiety, sleep apnea and narcolepsy are linked with an illness caused by infection in the lymphoid tissues over and above the brain.
I tried to get a copy of the study on which this commentary is based, and it available only to employees of the journal Medical Hypotheses. However, other journals such as Proceedings of the National Academy Sciences, Science and Nature are available.
In 2011, Dr. Almeida-Souza and colleagues in Brazil published findings claiming that the use of antidepressants for five years doubled the risk of serious heart problems. They suggested that the antidepressants were not affecting actual heart. But this is another case of a sleep-brain brain disorder – an autoimmune where the brain and central nervous system reject a substance
adderall and xanax for adhd that the immune system has made from one's own cells.
But we have to remember that the idea of immunological brain diseases was introduced into biology as a theory in 1980, long before the idea of autoimmune disorders.
In their review article, Drs. David Kessler and Michael Siegel in the July 2005 issue of Journal the American Medical Association wrote, "In contrast with immunological diseases, the immune system is not understood to play a major role in psychiatric illnesses." And there is an argument that these disorders do not respond to drugs such as Zoloft (Prozac), Mirtazapine (Remeron) adderall for depression and fatigue and Selincro. But, Dr. Kessler Siegel added, "In light of advances in understanding the biology of psychiatric disorders and the growing evidence of role immune system in these disorders, further investigation into this area is warranted."
The idea that sleep disorders are being caused by an immune insult from the system could hold key to explaining why people who take stimulants for sleep problems feel better, and why people who are taking antihistamine drugs do not. The mechanism by which caffeine lowers the blood sugar is by inhibiting a particular enzyme that makes histamine and its "dangers" come into being. I believe antihistamines and caffeine also work by blocking serotonin, the neurotransmitter that has potential to affect the brain and central nervous system.
In one of the most exciting developments, Dr. Siegel and other scientists have been studying how drugs that target these different neurotransmitters (serotonin, norepinephrine, acetylcholine and dopamine) will affect the sleep disturbances of people taking them for sleep problems.
To have sleep, you need serotonin, and people who have sleep problems also tend to have low levels of serotonin, so they have fewer of the neurotransmitters that make a person feel sleepy, say the scientists. One drug, called Trazodone (Vivitrol), blocks serotonin. So Dr. Siegel and his team studied the effect of drug on sleep in people taking Vivitrol. They saw a clear increase of the sleep time people who had problems. And the number of symptoms trouble falling asleep, including sleepwalking, decreased following drug treatment.
These medications may produce fewer side effects in people who get high doses, including insomnia, since the extra serotonin is being used directly to block the effects of sleep disorders.
In my view, there is more to sleep than the brain. Many other drugs, from hormones to antibiotics and antidepressants, can do Adderal 360 pills $985.51 $2.74 affect the brain, including sleep as they affect the rest of body. There will be an ongoing struggle.
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